Article provided by: Silver Fern Chemical LLC

Pluronic

Products that stick to their containers are less desirable than those that do not.  Pluronics, also known as poloxamers, are both hydrophilic and hydrophobic compounds used as emulsifying agents, in tissue engineering, and in cosmetics to help dissolve other compounds in water. The wide number of use cases of different Pluronic compounds makes them one of the most desirable compounds on the market.

How do Pluronics work?

The medical and cosmetic world embrace poloxamers for many solutions. Pluronic-F17 helps inhibit surface-tissue adhesion and Pluronic-F68 helps compounds avoid sticking to containers.

As both a hydrophobic and hydrophilic compound, poloxamers help bind to chemicals while remaining in liquid form. This property is used in contact lens cleaners to pick up unwanted substances.

How can Pluronics help my cosmetics dissolve in water?

When chemicals bind to substances, they often lose the ability to bond to other ingredients. This is due to the way that the atoms in the chemicals attach to other components.

Molecules can only bond to others in a limited way. Once a bond is formed, the ability to recombine declines drastically. Pluronics, while also acting to limit adhesion, can also bond to substances in a way that allows them to bond to water more efficiently.

The past few years saw the rise of non-soluble drugs with the help of compounds such as poloxamer 407. Cosmetic compounds requiring a liquid form benefit from this property as well.

Are there uses of poloxamers beyond acting as a barrier between substances?

These compounds are multipurpose. The types of pluronics used in the medical field also perform well as scaffolding for hematopoietic stem cells and lung tissues. They provide structure and help control how compounds bind.

This compound is also useful in drug delivery. Poloxamer 407 and poloxamer 108 improve the rate at which certain drugs take effect.

Studies even found pluronics to be an anti-carcinogen. Overall, the chemical is safe for ingestion. This makes it perfect for use in consumables, drugs, and replacement tissues. Studies on short-term ingestion found no adverse effects on animals.

Do Pluronics only come in paste form?

Poloxamers take many forms. They can be liquids, pastes, or solids. The ability to act as a barrier in any form makes this compound among the most desirable in cosmetics manufacturing, medical research, and in the bioengineering of tissues.

How can I keep Pluronics from degrading?

While useful, Pluronics tend to degrade quickly. They are often paired with an amino acid to improve the rate of degradation. Ultraviolet radiation is commonly used to link poloxamers with acids without significantly damaging the compound.

Bulk Providers of Pluronics in North America

Silver Fern Chemicals Inc. leverages a global supply chain to acquire and distribute compounds at the lowest possible cost. Our network of partners works with us to create a strong and stable supply chain.

Our experts offer a variety of Pluronics in bulk to help control costs. Get in touch with our team today to establish a supply of this vital material.

 

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